Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0317658
PubChem CID
Molecular Formula
C9H8N4O5
Molecular Weight
252.186 g/mol
Synonyms/Alias
[CHEMBL324161; SCHEMBL6571246; NYNKICKUYWHEGX-UHFFFAOYSA-N; 4-(Aziridin-1-yl)-3;5-dinitrobenzamide]
InChI Key
NYNKICKUYWHEGX-UHFFFAOYSA-N
InChI
InChI=1S/C9H8N4O5/c10-9(14)5-3-6(12(15)16)8(11-1-2-11)7(4-5)13(17)18/h3-4H,1-2H2,(H2,10,14)
IUPAC Name
4-(aziridin-1-yl)-3,5-dinitrobenzamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

18 19 0 0 0 0 0 0 0 0999 V2000
-3.6547 0.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.6547 -0.7500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.3557 -0...

Experimental Data

Activity Data

Target Ion Channel
Glutamate receptor ionotropic subunit NMDA 2B
Uniprot Accession Number
Function
Negative Allosteric Modulator
Species
Mus musculus (Mouse)
IC50
IC50: 1280 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
4 °C
Test Method
Binding assay
Test Species
Not specified

Binding Information

Binding Site
Extracellular domain
Binding Site Residue
ifenprodil binding site

Disease Information

Related Disease
P4

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
18
Rotatable Bonds
4
logP
0.4219
Complexity
60.4817
TPSA (Ų)
132.38
H-Bond Donors
1
H-Bond Acceptors
6
Ring Count
2
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